Transcranial Magnetic Stimulation (TMS) at Mind Spa Denver is an FDA‑approved, non‑invasive treatment for adults with major depressive disorder who have not improved enough with antidepressants or psychotherapy alone. By using focused magnetic pulses to stimulate mood‑regulating areas of the brain, TMS offers a drug‑free option that can reduce depression symptoms with minimal side effects and no anesthesia or downtime.
What is Transcranial Magnetic Stimulation?
Transcranial Magnetic Stimulation (TMS) is a form of neuromodulation that uses a magnetic coil placed over the scalp to deliver brief, targeted magnetic pulses to the dorsolateral prefrontal cortex, a brain region involved in mood and emotional regulation. The magnetic pulses create small electrical currents in the cortex, which increase neuronal activity and are believed to modulate key neurotransmitter systems, supporting healthier communication within mood networks.
How does TMS work in the brain?
Repeated TMS sessions gradually change how neurons in the prefrontal cortex and connected limbic regions fire and communicate. Research suggests that TMS:
- Increases cortical excitability in underactive mood circuits
- Modulates neurotransmitters such as serotonin, dopamine, and norepinephrine
- Promotes neuroplasticity and strengthens connections in networks involved in mood, attention, and cognitive control
These neuroplastic changes are associated with reductions in depressive symptoms, better emotional regulation, and improved overall functioning for many patients with treatment‑resistant depression.
Who is a good candidate for TMS?
TMS at Mind Spa Denver is intended for adults who:
- Have a diagnosis of major depressive disorder
- Have not responded adequately to at least one or two antidepressant medications
- Cannot tolerate medication side effects, or prefer a non‑drug treatment option
- Continue to experience low mood, loss of interest, fatigue, or poor concentration despite therapy
TMS may also be considered as part of a comprehensive plan for people with comorbid anxiety or PTSD symptoms when depression is a primary driver of impairment, based on individual evaluation and current clinical guidelines.
What is the TMS treatment experience like?
TMS treatments are performed in an outpatient setting at Mind Spa Denver, and patients remain awake and alert for the entire session. During each treatment:
- A TMS coil is positioned over the left dorsolateral prefrontal cortex
- You sit in a comfortable chair and may hear clicking sounds and feel tapping sensations on the scalp
- Sessions typically last about 20–30 minutes, once per day, 5 days per week
A standard acute course often involves 4–6 weeks of sessions, followed by a taper phase as needed, with schedules customized to your clinical response and insurance guidelines. Most people drive themselves to and from appointments and return to regular activities immediately after each session.
What side effects and risks should patients know about?
TMS is generally well‑tolerated and does not require anesthesia or sedation. The most common side effects are:
- Mild scalp discomfort or tapping sensation during treatment
- Temporary headache after a session
- Rare, brief lightheadedness
Serious risks, such as seizure, are rare when TMS is delivered according to established safety protocols and screening guidelines. Before starting, the Mind Spa team completes a thorough evaluation to review your medical history, medications, and any factors that might affect safety or eligibility.
What results can patients expect from TMS?
Clinical trials and real‑world data show that TMS can significantly reduce depressive symptoms in many people who have not responded to medication, with response and remission rates substantially higher than continuing medications alone in this population. Improvements may include:
- Brighter mood and more interest in daily activities
- Better energy and motivation
- Improved concentration and cognitive clarity
- Reduced hopelessness and emotional numbness
Some patients begin noticing changes within the first 2–3 weeks, while others experience clearer benefits closer to the end of the treatment course. At Mind Spa Denver, TMS is integrated with other interventional and psychotherapeutic modalities—such as ketamine infusion therapy, Hyperbaric Oxygen Therapy (HBOT), and talk therapy—to support durable, long‑term recovery rather than short‑term symptom suppression.
Start TMS treatment at Mind Spa Denver
If you are living with depression that has not improved enough with medications or therapy, Transcranial Magnetic Stimulation at Mind Spa Denver may be an appropriate next step. The team will review your history, discuss potential benefits and risks, and create a personalized treatment plan that fits your clinical needs and schedule.
Clinical References:
- George MS, Lisanby SH, et al. (2010). Arch Gen Psychiatry
- Carpenter LL, Janicak PG, et al. (2012). Depress Anxiety
- Berlim MT, Van den Eynde F, et al. (2014). World Psychiatry
- Dunner DL, Aaronson ST, et al. (2014). J Clin Psychiatry
