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Immersive Ketamine Therapy


Ketamine Infusion Therapy at Mind Spa Denver is an advanced treatment for adults facing treatment‑resistant depression, PTSD, anxiety, and suicidal ideation when standard care has not been enough. By combining low‑dose IV ketamine with vibroacoustic therapy on the Sound Lounge 3 and immersive AI‑generated art, Mind Spa offers a uniquely multisensory experience that supports both rapid symptom relief and deep emotional processing.

What is Ketamine Infusion Therapy at Mind Spa?

Ketamine Infusion Therapy uses low, carefully controlled doses of ketamine delivered intravenously in a calm, clinically monitored environment. Unlike traditional antidepressants that primarily target serotonin, ketamine works through the glutamate system and NMDA receptors, promoting rapid changes in brain circuits involved in mood, trauma, and stress regulation.

How does ketamine work in the brain?

Ketamine increases glutamate signaling and boosts brain‑derived neurotrophic factor (BDNF), a key protein for neural repair and synaptic plasticity. This surge in neuroplasticity supports the growth and reconnection of pathways in regions such as the prefrontal cortex and hippocampus, which are often disrupted in depression and PTSD. As a result, many patients experience meaningful relief in hours to days rather than weeks.

Who is this treatment for?

Mind Spa’s Ketamine Infusion Therapy is designed for people who:

  • Have not responded to at least two antidepressant medications
  • Live with treatment‑resistant depression, PTSD, generalized anxiety, or severe, persistent symptoms
  • Experience suicidal thoughts or feel stuck despite therapy and medication

For those who feel like nothing else has worked, ketamine can create a crucial opening for change and renewed engagement in life.

What is the patient experience like?

Each session takes place in a quiet, spa‑like room where you rest in a comfortable recliner while ketamine is infused slowly through an IV over 60–90 minutes. Throughout the infusion, your vitals are continuously monitored by trained clinical staff to help ensure safety and comfort.

  • Initial course: 6 infusions over 2–3 weeks
  • Maintenance: Booster infusions approximately every 4 weeks or as clinically indicated
  • Sensations: Many patients describe a “floaty,” dream‑like, or mildly dissociative experience that fades shortly after the infusion

Common side effects such as lightheadedness, nausea, temporary dissociation, or brief increases in heart rate or blood pressure are usually mild and short‑lived. Most patients can resume typical activities within a few hours, with appropriate guidance from the care team.

Vibroacoustic therapy and AI art: a one‑of‑a‑kind ketamine experience

To deepen the therapeutic effect, Mind Spa integrates vibroacoustic therapy using the Sound Lounge 3 during ketamine sessions. This technology delivers music and sound as gentle vibrations through the body, helping patients relax, regulate their nervous system, and feel more grounded while engaging in the ketamine experience. The synchronized sensory input can support emotional release, body awareness, and a greater sense of safety during altered states.

Mind Spa also incorporates AI‑generated visual art to create a personalized, immersive environment that reflects and captures elements of a patient’s inner experience. These visuals can help patients engage more intentionally with insights, emotions, and imagery that arise during the infusion, turning each session into a unique, meaning‑rich journey. Together, ketamine, vibroacoustic therapy, and AI art make Mind Spa’s protocol a one‑of‑a‑kind, multisensory approach to interventional psychiatry.

What results can patients expect?

Research shows ketamine can produce response rates of up to around 70% in treatment‑resistant depression, with noticeable improvements often appearing within 24–72 hours after an infusion. Many patients report reductions in suicidal ideation, lighter mood, decreased anxiety, and more emotional flexibility, especially when treatment is paired with ongoing support.

At Mind Spa Denver, ketamine is not a standalone intervention; it is integrated with Transcranial Magnetic Stimulation (TMS), Hyperbaric Oxygen Therapy (HBOT), and psychotherapy to stabilize gains and turn short‑term neuroplastic changes into lasting recovery. Many patients completing the full initial series describe a level of relief and possibility they have not felt in years.

Start your healing journey at Mind Spa Denver

If you have tried multiple medications and therapies and still feel stuck, Ketamine Infusion Therapy at Mind Spa Denver, with its blend of medical precision, vibroacoustic technology, and immersive AI art—may be an appropriate next step. Completing the clinic’s secure new patient forms allows the care team to review your history, discuss risks and benefits, and collaborate with you on whether this integrated ketamine protocol fits your goals and overall treatment plan.

Selected Research Citations:

  1. Zarate, C.A. et al. (2006). Arch Gen Psychiatry
  2. Price, R.B. et al. (2009). Biol Psychiatry
  3. Murrough, J.W. et al. (2013). Am J Psychiatry
  4. Abdallah, C.G. et al. (2015). Neuropsychopharmacology
  5. Duman, R.S. & Aghajanian, G.K. (2012). Science

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